A friend just sent me this, and I had to re-post. It speaks for itself.

Artist Timothy Lim swapped out Bill Watterson's mischievous boy and stuffed tiger with Peter Parker and his unruly symbiote. Aww, Venom is so cute when he's trying to munch Peter's skull! Lim's images are also available on t-shirts.

As both a Spidey and Calvin & Hobbes Fan, I totally love this.